Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16774 Roscovitine GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 41 CBX5; FOXD1; RRN3; NCOA6; BLM; JARID2; BTG1; MEF2A; BRD2; KAT7; ZMYND8; MED24; SATB2; KLF10; BCLAF1; FOXC1; AFF1; CHD7; POLR2A; ELF1; SFPQ; MKL2; BATF; HMGB2; JUP; RORA; ZBTB1; PAX5; TGIF1; JUNB; RREB1; TOB1; FOSL2; HMGB3; MYT1L; IRX5; CITED2; BHLHE40; NR2F2; TXNIP; ZEB2
Down-regulation 74 IFI16; ANKRD1; HOXA5; ID3; SIX1; ZNF22; ZEB1; ZKSCAN7; NR2F1; PAXBP1; ZNF32; CTBP2; PRRX1; ST18; ACTL6A; ZNF195; YEATS4; ING4; SNAI2; SALL2; CREB3; SIM2; TDP2; NFATC4; HOXD1; DACH1; ILF2; BANP; ZNF124; ZNF532; TULP3; EHF; ID1; E2F5; MECOM; RBPJ; ARNT2; EMX2; TCF7L2; HDAC9; SMARCA1; ZFHX4; NFIB; LMCD1; ZNF232; WWTR1; NFE2L3; BHLHE41; CITED1; ZNF160; REL; SOX2; STAT1; HOXB2; MEOX1; TBX3; SOX11; ZNF652; TCF21; ZFPM2; TOX; HEY1; CRK; AEBP1; TRIM29; MXI1; EGR2; ZIC1; ELF5; TFAP2C; ZNF586; IKZF1; CEBPA; PAX8