Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16773 Roscovitine GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 27 BTAF1; NCOA6; EDF1; HIVEP2; DDX5; FOXN3; TSC22D2; MYB; SERTAD2; SATB2; CEBPA; RXRA; BCL11B; INSR; SMAD1; ZBTB18; TCF7; ZNF281; SOX4; KLF2; MXI1; PBX3; RUNX3; LEF1; MSX1; CREB1; CRK
Down-regulation 22 USP22; IRF9; SALL2; ZNF532; C1D; TRIM22; CRYM; RBBP8; CUX2; AHR; TRIB3; ZBTB20; TCF21; MEIS1; EYA1; MNDA; SAP30; ZNF423; ZIC1; HOXB2; ESR1; EGR2