Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16771 Roscovitine GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 38 RFX5; E2F3; SMARCA2; CREB3L2; MTF2; ZNF443; NCOR2; BRCA1; CUX1; TSC22D1; NCOA1; CBX6; PAX8; FOSB; HEY2; FLNA; ZIC1; SOX10; LMCD1; NFIB; TRPS1; EMX2; HLTF; NR2F2; PEG3; ELK3; ID1; JUND; ZBED2; TXNIP; FOS; EYA2; ESR1; ZNF91; MAF; BASP1; HOXC6; CRK
Down-regulation 38 ADNP2; TOX3; TGFB1; TP63; PCGF1; RORA; TCF21; TRIB3; CREM; ZNF329; ERG; KLF10; ZBTB1; RBL2; GATA6; FOXF2; POU2AF1; CUX2; TRIM22; MNDA; FOXF1; ZBTB20; SOX2; FOXA1; NR4A3; PAX5; TWIST1; IRF7; ARNT2; ISL1; SATB1; MEIS2; AEBP1; TOX; RUNX3; MYRF; CREB1; IKZF1