Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16769 Roscovitine GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 35 SUV39H1; ZMIZ1; SSBP2; PQBP1; NFIC; RFX5; AR; BRD4; ZNF589; HDAC1; TRIM24; TGFB1; EGR1; PFDN5; SUB1; MYCN; CCNC; TWIST1; HMGN3; FOXE1; PIR; TCF7; CEBPA; MAGED1; ASCL1; DNMT3B; THAP11; FOS; HOXC6; PITX1; ZIC1; LEF1; EYA2; ESR1; ATF3
Down-regulation 48 ADRB2; BACH1; CHD7; TGIF1; CHD1; CDK8; NFYB; PAXBP1; GABPA; GFI1; SMAD4; MNDA; SIX3; HMGB2; MKL2; ATF7IP; NFAT5; ERBB4; ZNF266; FOXO1; MYRF; KLF11; NFE2L3; ZNF232; NRBF2; CENPF; VDR; SATB1; YBX3; ZEB2; TBL1X; RBBP8; KLF6; TLE4; ZHX2; TCF21; IRF4; HLX; ZNF423; BACH2; SAP30; AEBP1; FLI1; ZBED2; TRIM29; SOX11; CREB1; WT1