Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16767 Torin-2 GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 57 GATA2; TSC22D3; NFATC3; KDM5B; NR3C1; PHF2; PAWR; FOXC1; MTF2; FOXN3; ARID4A; HDAC1; CHD9; HBP1; TLE4; ARID5B; PHOX2B; PRKDC; SMAD2; ID2; ZFHX3; TBL1XR1; NFIL3; SMARCA2; AFF1; HMGA1; TBX2; NCOA4; RBPMS; SOX4; HMGB3; MEF2A; SATB1; TP63; HOXC10; RBBP8; HSBP1; ZNF281; EYA1; KLF2; TBX3; MYB; SMAD7; BHLHE41; FOXF1; FOXG1; SAP30; TLE1; KLF9; MECOM; KLF4; MAF; MAFB; HOXC6; ATF3; FOS; CRK
Down-regulation 67 SUB1; FOSL1; IRF3; ZNF85; ZNF692; HOXA10; PRDM12; SCAND1; NHLH2; UBE2I; ZNF248; RFXANK; ZNF239; AR; ZBED2; TRIB3; CITED1; ACTL6B; MYRF; CUX2; NR5A2; ATN1; IRF1; NEUROD1; ZIC3; NFE2L3; WWC1; HDAC9; ZFPM2; CEBPZ; ZNF43; NFE2; SALL2; BNC2; WT1; NR2F1; ZNF711; PLAGL1; HOXB2; AEBP1; NR0B1; CTBP2; IL16; HIRA; SOX10; HIC2; VPS72; LOXL2; IRF4; SOX2; SOX17; GATA6; EGR1; ESR1; KLF10; DNMT3B; BCL11A; ZBTB18; ST18; ZNF423; CREB1; ZIC1; BHLHE40; ID4; EGR3; ARNT2; CEBPA