Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16765 Torin-2 GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 54 TSC22D3; NR3C1; TCFL5; KDM5B; FOXO3; ADRB2; HBP1; HDAC5; JUP; CITED2; TP63; PNRC1; IFI16; YEATS2; SLC2A4RG; ZBTB16; BRD8; ARID4B; DDIT3; IRF8; TRIM22; NCOA2; ERBB2; ELF1; RBPMS; IKZF1; IRF4; RORA; GATA3; ZNF217; BTG1; HOXC4; SOX4; TXNIP; TFAP2C; PPP1R13L; RBL2; POLR2A; HMGN3; MYB; BASP1; TLE4; HOXC6; ZNF160; ARID5B; POU2AF1; CEBPA; IRX5; ZKSCAN1; PIR; MAF; PAX5; ZEB2; CRK
Down-regulation 89 FOSL1; E2F3; HOXA10; E2F6; ZNF32; ZFP37; ST18; EGR1; PAX6; POLR3F; NUP62; NHLH2; ABT1; MYT1; NEUROD1; HMGA2; PROX1; TDP2; INSM1; CDK8; JUN; MAX; ZNF22; DACH1; ZNF552; WDR77; PPRC1; ZFP69B; ZKSCAN7; SIX1; ZNF211; TEAD1; ZNF24; GTF3A; NFAT5; EGR4; ZNF331; RFXANK; HEY1; SALL2; TEAD4; ZNF43; CCNE1; GATAD2A; RBFOX2; ZIC3; MEIS1; ILF2; CAMTA1; CRY1; TGFB1I1; ETS2; ID1; ZFHX4; NR4A2; MYCN; EHF; ZNF711; EMX2; VPS72; SIX2; PRRX1; ELK3; SOX11; JUNB; EGR2; BHLHE40; ISL1; HIRA; MEOX2; ZFP36L1; ZIC1; NKX3-1; TLE1; DLX5; ZEB1; NR4A3; LMCD1; MSX1; TOX; CRYM; MEIS2; TSC22D1; MECOM; HOXB2; ZBTB18; WT1; FOS; CREB1