Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16763 Torin-2 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 51 TSC22D3; NR3C1; ID2; HBP1; NFKBIA; TCF25; RELB; FOXO4; EZH1; BTG1; CITED2; MZF1; HDAC5; CEBPD; CALCOCO1; BRD8; NR1H3; SREBF1; ZNF532; SOX4; PSPC1; NFIL3; SP140L; STAT6; IRF8; PAX5; PNRC1; FOXO1; CEBPB; IRF1; TRIM22; CBX7; ZNF217; RERE; BCL3; RBPMS; ZNF611; TGFB1; LITAF; CALR; JUP; POU2AF1; TLE1; TRIP6; CEBPA; MYB; BCL11A; MXI1; HOXC6; KDM5D; CRK
Down-regulation 73 FOSL1; HMGA2; MYC; ADRB2; ATF5; NKRF; EGR1; YAP1; HOXA10; AFF4; ETS1; E2F3; NUP62; EED; NFAT5; RNF138; E2F6; JUN; PROX1; CRY1; MYT1; HIVEP1; ZNF529; SOHLH2; MGA; HMBOX1; ZNF239; DEK; TFAM; NR3C2; TEAD4; ZFP36L1; MYBL1; TAF1A; KLF4; TSC22D2; BIRC2; EGR3; NR4A3; ZEB1; CBFB; SUB1; CUX2; SOX11; ST18; OLIG2; NKX2-2; LEF1; ETS2; EGR2; PEG3; TSC22D1; FOXE1; WWC1; CREM; MEOX1; SALL1; MEIS1; ELK3; SATB2; GTF3A; ATF3; ZFPM2; TBX3; FOSB; SNAI2; ZBTB38; NR4A1; PBX1; SATB1; EMX2; FOS; PAX8