Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16762 Pelitinib GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 71 TSC22D3; VGLL4; ZNF274; SMAD2; TUB; HMGB1; ING3; ID2; FOXJ1; HDGF; TCF15; RFX5; PEX2; YEATS4; LDB1; ZSCAN31; LMCD1; MXD4; TFDP2; CDX1; NR1D2; CARHSP1; TFAM; ARID5B; CRYM; NFIL3; RBBP4; PIAS2; SSBP3; IKZF1; SPIB; HMGN3; ZIC3; TULP4; ZNF165; TOB1; BHLHE40; SMAD6; TRIM29; HOXD3; HMGB3; MYT1L; RBL2; ZIC1; MYCN; NFATC1; PIR; CTBP2; CREM; MYB; GATA6; LIN28A; ID3; TOX; OSR2; MEIS1; HMGB2; WNT4; DNMT3B; BTG1; INSM1; HOXD1; JUND; FOXF1; PAX5; HOXC6; BCL11A; NR4A2; FOS; WT1; CRK
Down-regulation 76 FOSL1; MYC; HES1; HMGA2; ETV5; FHL2; IKBKAP; IRF1; MAFF; EGR1; SIN3B; TGFB1; MNT; ZNF593; WWTR1; CIZ1; FLNA; ZFP36L1; GTF2I; EGR3; PPRC1; ARNTL2; FOXD1; HHEX; MED21; PMS1; SOX9; CAPN15; ADRB2; HDAC4; MGA; CAMTA2; TAF1A; TRIB3; TGFB1I1; EGR2; ELK3; ZNF512B; KLF10; NELFB; HDAC9; PEG3; CBX6; SIAH2; MYBL1; LOXL2; NKX2-2; IRF8; SATB1; RXRA; PITX1; ZEB1; ZEB2; SHOX2; HOXB2; KLF11; FOXC1; TWIST1; BHLHE41; MAF; AHR; BAZ1A; INSR; ZBED2; HIPK3; ST18; NR2F2; IRF7; ID4; MNDA; TFAP2C; SOX11; ATF3; MAFB; PAX8; CEBPA