Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16761 Pelitinib GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 73 TSC22D3; ID2; ZNF274; TCFL5; NR3C1; PTTG1; TCF4; TOB1; ID3; TFDP2; ZSCAN31; NFIL3; IRF4; TP63; HDAC5; ZSCAN18; BRD8; TBL1XR1; FOXE1; BHLHE41; XBP1; ZNF226; MITF; PSMC3; CEBPG; SMARCA2; NR3C2; HHEX; SPIB; PAWR; IRF6; NCOA2; HSF2; NR1H3; ZFPM2; HSBP1; CTNNB1; CTBP2; JUP; MAF; IL16; HMGB2; OSR2; SALL1; BTG1; BACH2; MYCL; PAX8; JAK2; PNRC1; LITAF; HLTF; TRIM29; CEBPA; TGIF1; AFF1; POU2AF1; TLE1; BCL11A; RXRA; PBX3; MYB; PIR; PAX5; TXNIP; BHLHE40; ATF3; ZHX2; EMX2; ESR1; ID4; HOXC6; LEF1
Down-regulation 64 FOSL1; MYC; EGR1; HES1; HMGA2; TGFB1; EGR4; PPRC1; CAPN15; EGR3; ETV5; MAFF; BAZ2A; CENPB; SF1; BCL10; NFAT5; MSC; CAMTA2; RCOR1; MYBL1; NR2F1; ACTL6A; FOXG1; YAP1; ZBTB38; PLAGL2; ZNF281; TWIST1; TAF9B; BRD4; KLF10; NFIC; SOX9; BCL3; CBFB; JUN; SHOX2; JUNB; FOSB; ETS2; ZNF232; HMGA1; SMAD5; RUNX1; AHR; TCF7; EGR2; MYRF; PAX6; MEIS2; ELK3; BAZ1A; ELF3; TOX; LOXL2; CRYM; ZFP36L1; KLF2; HOXB2; FOS; HEY1; SMARCA1; CREB1