Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16760 Pelitinib GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 25 TSC22D3; XBP1; ID2; NFE2L1; SLC2A4RG; TADA3; NFIL3; HMGN3; TFDP2; PBXIP1; KAT6B; RBBP8; IRF9; RORA; SNAI2; PSIP1; DNMT3B; CEBPA; TWIST1; TOX; BCL11B; TLE1; MXI1; HOXD1; BHLHE41
Down-regulation 48 FOSL1; MYC; HMGA2; ATF5; HMGA1; MAFF; DNAJC2; EGR1; SOX9; HES1; TRIM27; FOXC1; PDLIM1; TRIB3; TAF1A; JUNB; GTF2I; HHEX; MNDA; FLNA; ADRB2; TBL1X; KLF10; LOXL2; SIX2; EGR3; ERBB4; BCL3; ARID1A; RUNX1; FOXD1; ZFP36L1; ELK3; BASP1; FOSB; EYA2; ELF5; SOX11; SATB1; KLF11; BHLHE40; ZEB2; NR2F2; NR4A2; MYT1L; KDM5D; EGR2; PAX8