Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16759 Pelitinib GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 53 PPARG; GATA2; TSC22D3; ZMIZ1; ID2; ZNF274; DDIT3; NR1H3; IRF5; MED7; TBX2; IRF9; PIR; XBP1; NFIL3; SMAD6; HMGN3; PSMC3; PNRC1; ZNF200; TXNIP; ID3; BHLHE40; MTF2; MYB; SMARCA2; CEBPB; TLE4; JAK2; HMGB3; NR2F2; JUP; OSR2; MNDA; BTG1; BASP1; ARID5B; ELF1; AFF1; EYA1; TOB1; TLE1; HIPK3; CRYM; RXRA; BHLHE41; FLI1; SAP30; MECOM; ZEB2; WT1; HOXC6; CRK
Down-regulation 59 FOSL1; MYC; HMGA2; EGR1; CENPB; PPRC1; MAFF; POLR3F; PAXBP1; DDX17; ZNF654; E2F5; NEUROD1; CHD7; NHLH2; CAPN15; YWHAB; PRKDC; INSM1; ZKSCAN7; SATB2; MAFG; ZNF133; FOSB; NKX2-2; LOXL2; ZNF43; NFIC; IRF1; WWTR1; SHOX2; SERTAD2; GTF3A; JUN; BCL3; CBFB; ELK3; SOX9; PAX6; LIN28A; ZFP36L1; MLXIP; SMARCA1; BACH2; JUND; SOX11; MEIS1; ST18; SOX2; SMAD1; HOXB2; HEY1; PEG3; PITX1; ESR1; MYRF; MEF2C; CREB1; IKZF1