Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16758 Pelitinib GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 47 TSC22D3; ZMYM2; ING3; BRD8; BRD3; PPARGC1A; IRF5; JARID2; RBL2; XBP1; PSPC1; ARID4A; TRIM32; ID2; BLM; TOB1; IKZF1; RORA; ESRRG; TWIST1; PIR; HMGN3; TXNIP; IRF4; TBX2; TLE4; ELF1; ZBTB1; BASP1; SMAD6; TLE1; PSIP1; AFF1; PURA; HLTF; SATB1; DNMT3B; RXRA; CEBPA; MAGED1; SAP30; RBPMS; HOXB6; TOX; HOXC10; HOXC6; CREB1
Down-regulation 43 FOSL1; MYC; HMGA2; CREG1; MAFF; HOXA5; EGR1; SOX9; TGFB1I1; NPAS2; TERF2; ESR1; RUNX1; ERG; CLOCK; FOSB; ZNF652; ADRB2; JUN; KLF5; TSC22D1; NKX3-1; LITAF; JUNB; WWC1; ETS2; KLF6; ST18; DLX5; CRK; PEG3; NR4A1; SOX2; ZEB1; ZNF91; KLF2; EGR3; MEIS2; EGR2; BCL11A; ZHX2; FOS; MYRF