Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16757 Pelitinib GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 60 ZNF274; ID2; ING3; ZNF410; TFDP2; HOXC4; PIAS2; CNOT2; MAZ; ZSCAN18; SUMO1; ZNF606; PHOX2B; TBL1XR1; HOXD11; AFF1; GATA3; PAX8; ERBB2; GTF2IRD1; TSC22D2; TBX3; ZNF165; HMGN3; BBX; TAF10; CERS4; SPIB; ZNF329; MBD2; SAP18; HOXC6; HOXC10; ZNF91; PTTG1; WWC1; SALL1; ATF3; YBX1; SMAD6; CITED1; MAFB; NR0B1; ID3; MEOX1; CENPF; HEY2; SATB1; TRPS1; OSR2; SOX4; NR2F2; MXI1; PIR; TRIM29; BASP1; EMX2; CREB1; MAF; ID1
Down-regulation 71 MYC; FOSL1; TFAP2A; HMGA2; ADRB2; EGR1; ETS1; HES1; CEBPD; EGR3; SNAI2; TGFB1; FOXA2; RUNX1; POU4F1; MAFF; KLF1; TRIB3; VDR; MNDA; NFE2L3; KLF2; KAT2B; SP140L; NFE2; HOXB6; ETS2; KLF10; SERTAD2; ETV5; ZFP36L2; RREB1; DMTF1; FOXF2; CBFA2T3; TP63; ZEB1; NR4A2; TOX3; ERG; STAT4; TCEA2; HOXA5; NR4A3; MYBL1; PLAGL1; NR4A1; NR2F1; HLX; KLF5; POU2AF1; FLNA; EGR2; DLX5; NRIP1; INSM1; BNC2; HOXD1; EHF; MYRF; ZNF281; SMAD7; BCL11A; TSC22D1; FOXF1; ZEB2; KDM5D; TOX; MEIS2; ARNT2; CEBPA