Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16756 Azd-6482 GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 41 CERS6; TCF12; HTATIP2; KAT6B; FOXF1; MYB; FOXD1; TBX2; CDX1; SMAD2; SMAD6; NR3C2; MITF; TGFB1I1; ZNF587; NFE2L3; TCF21; FOXF2; DACH1; NR2F2; REPIN1; ERG; IRF7; ZEB1; HOXB6; ZFHX4; IRF4; TOX3; OSR2; KLF5; SATB2; NR4A2; ZBTB20; JUP; AHR; ZKSCAN1; BASP1; PIR; KDM5D; CREB1; CRK
Down-regulation 38 MED21; PA2G4; NFIB; RAN; ZNF415; ZNF43; CREB5; ZIC1; NEUROD1; TAF9B; PEG3; CALR; SCAND1; CD3D; ZNF711; SOHLH2; BHLHE41; STAT4; HOXC4; HLF; YBX3; ELF5; MYBL1; ZNF83; SMARCA1; JUND; ZBED2; SATB1; MXI1; EMX2; EYA2; FOXG1; SOX17; FOS; ID4; HOXC6; PAX8; IKZF1