Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16755 Azd-6482 GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 30 MBD2; RBBP5; CARM1; ECD; JARID2; TSC22D2; YWHAB; TBX2; TRIM32; MEF2A; PTTG1; MTF2; PURA; PIR; ELF1; ZBTB16; LEF1; EMX2; NR2F2; BCL11B; ZFP36L2; ZNF512B; MSX1; TSC22D1; ID4; MAF; MAFB; HOXC6; WT1; CRK
Down-regulation 46 SUZ12; ATF5; DDIT3; UBE2L3; SIX2; SIX1; ARNTL2; PAX6; TRIB3; LIN28A; FOXN3; SALL2; STAT6; LYL1; PBX3; CUX2; HIC2; ZNF544; NFE2; MNDA; TAL1; NFE2L3; TRIP6; FOSB; CRYM; CITED2; JAK2; ZIC1; IRF8; KLF4; ZNF652; ZNF423; ASCL1; INSM1; SHOX2; NR4A2; EGR2; CREB1; BCL11A; FLI1; BASP1; MYRF; MEF2C; ARNT2; IKZF1; CEBPA