Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16754	Azd-6482	GSE70138	MCF10A	Human	3h	0.37uM	EID0008

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	ZMYM2; HES1; TERF2; SSBP2; PSPC1; KDM5D; RCOR3; POU4F1; SMAD1; LMCD1; HCFC2; SMAD2; POU3F2; UIMC1; SSRP1; HMGB1; ZNF281; ZNF148; IRX5; ZNF107; SAP18; YAF2; FOXC1; ARNTL; ERBB4; SMARCA2; KLF2; TAF10; HOXB7; CNBP; MED1; ISL1; ESRRG; IKZF1; GATA3; MEF2A; TAF9B; TRPS1; GTF3A; SAP30; HEY2; PIAS1; SERTAD2; ZNF423; HOXB6; PAX5; HMGA1; KAT2B; ERG; MYB; HHEX; ZBTB18; NKX3-1; HMGB2; BRD4; MYT1L; HIPK3; MAGED1; TWIST1; INSR; ELF5; MAFB; GATA6; TOX; SMARCA1; SOX9; CREB1; ZEB2; SATB1
Down-regulation	68	IRF3; CREB3L2; IKBKAP; KDM5C; CSDC2; IRF9; ZSCAN31; ZNF124; ZNF551; ZNF224; NFKB2; GATAD2A; SOX15; CBX7; ZBTB20; TGFB1; LITAF; MED14; PTRF; TSC22D2; GFI1B; ZNF652; ZNF665; ID1; BNC2; L3MBTL1; RBFOX2; FOSB; NR4A1; HIC2; MYCL; CERS4; ZNF667; ZNF611; TRIB3; WWTR1; IRF8; MYCN; TP63; JUNB; ZBTB38; PLAGL1; CITED2; HMGB3; DLX5; RBPMS; ZNF160; CALR; SNAI2; PAX6; ZNF264; TLE2; CREM; TRIM16; FOSL2; DACH1; CRK; NR4A2; PBX3; KLF10; ST18; ZKSCAN1; TCF4; ARNT2; FOS; ID4; MEIS2; PAX8