Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16753 Azd-6482 GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 39 SPDEF; BRCA1; NRBF2; IRF4; BMI1; EGR2; KAT7; ZNF468; ID2; TBX2; ASH2L; SMARCA2; ZEB2; BATF3; RXRA; BACH1; AHR; ZNF217; TXNIP; HSBP1; SAP30; FLI1; BHLHE41; HLTF; KLF10; KAT2B; FOSL2; FOXD1; JAK2; HOXB7; EGR3; KLF2; KDM5D; TLE4; BASP1; MYB; FLNA; NKX3-1; CREB1
Down-regulation 66 RBFOX2; TGFB1I1; MEIS1; CNOT3; MAFG; NR2F6; PRDM12; TBX3; ZNF302; TGIF2; ESRRG; TCF7L1; CCNC; CDIP1; ZNF611; ENY2; ACTL6B; MXI1; SCAND1; ZNF721; ATN1; ZNF232; NFIB; SMAD1; FOSB; HEY1; TRIM29; MEIS2; ZNF91; CBX6; HMGA1; LOXL2; NEUROD1; ZNF160; ZFPM2; ESR1; BRD4; ZFHX4; TCF7; SHOX2; FOXF1; ARNT2; SMARCA1; SOX2; PEG3; TRPS1; TOX; ZBED2; JUND; SOX11; CRK; TLE2; INSM1; NR2F1; MYT1L; ZNF512B; TCF4; AEBP1; ELF5; ZHX2; TFAP2C; EMX2; FOXG1; FOS; CEBPA; IKZF1