Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16751 Azd-6482 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 52 TSC22D3; NR3C1; NCOA2; IRF5; BRD8; TRAK1; CALCOCO1; FOXO4; MAGED1; TXNIP; FOXC1; ID2; DEK; FOXN3; IRF4; BCLAF1; JUP; HBP1; MITF; HOXB6; IKZF1; MED1; SPIB; HOXA5; ZNF217; STAT5A; IL16; CIITA; PAX8; RERE; BASP1; ZMYND8; OSR2; HOXB7; ELF3; PAX5; PURA; BTG1; BHLHE40; CEBPA; TLE1; HOXC10; NR2F1; ZBTB38; IRF8; CITED2; MEIS1; TRIM29; AHR; RUNX3; WT1; HOXC6
Down-regulation 51 FOSL1; HMGA2; MAFG; PPRC1; ZFP69B; TGFB1I1; ZBED4; MAFF; E2F6; RNF138; TSC22D2; JUN; MED17; ZNF124; ERG; EGR4; SKIL; GATAD2A; EGR1; ZNF22; DACH1; ZNF112; NR0B1; OLIG2; INSM1; ZNF232; TSC22D1; NEUROD1; BAZ1A; ID1; HTATIP2; CUX2; HOXB13; HMBOX1; ETS2; SOX11; BCL11B; HLX; EGR3; SATB1; JUNB; NFIB; TWIST1; HEY1; CRK; MAFB; FOS; GATA6; MSX1; EGR2; CREB1