Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16750 Tgx-221 GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 48 ID2; TSC22D3; ID3; E2F8; SMARCD2; BPTF; SSX1; HMGN3; OSR2; PNRC1; RFX5; FOXN3; MBD2; TWIST1; TCF4; ID1; HBP1; AEBP1; BAZ2B; FOXG1; DNAJC1; ZNF232; CEBPB; NFATC4; KAT6B; TCF7L1; MECOM; EYA1; ZNF467; INSR; GTF3A; SMAD6; SMAD1; TLE4; SAP30; TFAP2C; ZHX2; ARNT2; TRIM29; SALL1; PBX3; MEIS2; POU2AF1; ARID5B; PBX1; HEY1; LEF1; CRK
Down-regulation 37 FOSL1; MYC; HMGA2; MAFF; EGR1; KLF10; HES1; EGR3; WWTR1; XBP1; EGR2; ELK3; PTRF; HMGA1; SOX9; SERTAD2; RREB1; CD3D; FOSB; ZNF160; NFAT5; AHR; BHLHE40; SATB1; NRIP1; BASP1; ZNF264; TOX3; NR4A2; ZBTB20; TFEC; ZBTB18; PEG3; NKX3-1; ZEB2; KDM5D; CEBPA