Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16744 Azd-8330 GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 60 ID2; TCF12; ID3; EZH1; CDK9; TSC22D3; CARHSP1; CSDC2; ID1; PAXBP1; ZFPM2; BTG1; ZNF500; BANP; SSX1; TWIST1; E2F8; IRF9; ZNF232; NR2F2; CEBPB; ZNF589; SMAD1; SMAD6; DNAJC1; PAX6; JUN; CEBPZ; OSR2; SOX2; HEY1; AEBP1; HIRA; MEIS1; MEIS2; HLF; ZBTB16; TCF4; ARNT2; MYCL; TULP3; COPS2; ASCL1; TCF21; LMCD1; ZIC1; CREB1; MECOM; FOXG1; CITED2; KLF9; ZHX2; FOXF1; MSX1; EMX2; PBX1; E2F2; ID4; POU2AF1; CRK
Down-regulation 47 FOSL1; MYC; FHL2; HES1; MAFF; EGR1; STAT3; E2F3; PRKDC; SMAD3; SOX9; PPRC1; EGR3; BCL3; URI1; ELK3; LPIN2; ZNF239; CHD7; IRX5; CREB3L1; ARID1A; NFE2; HLTF; ERG; ELF3; NRIP1; YWHAB; RUNX1; SMARCA2; STAT4; HHEX; NKX2-1; FOSB; FOSL2; AHR; TGFB1; BHLHE40; SATB1; ZBTB38; BAZ1A; ZEB2; KDM5D; ZBTB18; TSC22D1; FOS; CEBPA