Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16743 Azd-8330 GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 59 ID2; TSC22D3; ZMIZ1; MYNN; MYCL; CNBP; NHLH2; ZNF423; PLAGL1; SUB1; THAP10; BNC2; PNRC1; SIX3; ID3; GTF2IRD1; GATA3; YEATS4; HDGF; TGIF2; IRF1; KAT6B; ZNF536; ERBB2; SMAD6; HOXC4; BHLHE40; SCAND1; NFATC4; ID1; NR1H4; NR0B1; MBD2; SOX13; ZNF467; PBX3; TWIST1; MEIS2; TOX; ISL1; BRCA1; PAX6; SNAI2; POU2AF1; NANOG; MECOM; HMGB2; TLE4; FOXF1; FOS; JUP; ZIC1; INSM1; CREB1; SOX11; ZNF91; ATF3; ARNT2; MAFB
Down-regulation 37 FOSL1; MYC; FHL2; SMAD3; NR3C1; EGR1; FOXC1; HOXA10; BLM; EGR3; RUNX1; ARID4B; LOXL2; NCOR2; BAZ1B; RREB1; FOXJ3; ELK3; WWTR1; HTATIP2; FLNA; SPEN; NRIP1; NR4A2; THAP11; TLE1; AHR; SATB1; NR2F1; SATB2; SOX9; BASP1; EGR2; NR4A1; ID4; ZEB2; CEBPA