Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16742 Azd-8330 GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 56 TSC22D3; DAXX; BTG1; CERS6; ZNF589; CBX5; NR3C2; JUN; SIAH2; TBL1XR1; ID2; BBX; ZBTB16; TOX3; ZNF430; SAP18; ING2; PHF20; TFEC; INSM1; MYCN; BHLHE40; PBX1; CRYM; PEG3; ZKSCAN1; ZBTB38; TLE1; TBX3; BASP1; SMAD5; ELF1; PIR; NR2F2; RBPMS; MYRF; TOB1; KLF6; BHLHE41; TGIF1; NANOG; PLAGL1; ZNF423; ST18; LMCD1; SAP30; ZEB2; KDM5D; ZNF91; DACH1; HOXC6; MAFB; PBX3; ATF3; GATA6; CRK
Down-regulation 47 FOSL1; MYC; HMGA2; RUNX1; EGR1; SKI; CEBPB; SP140L; IFI16; E2F3; RFXANK; STAT1; ENO1; TGIF2; RBBP8; CBFB; ZNF195; SMARCD3; VDR; TFAP2C; NCOR2; AGO2; TRIB3; DLX2; ATN1; SATB1; MECOM; SCAND1; WWTR1; NKX2-1; RBPJ; HEY1; ZFP36L1; ZNF512B; NR4A2; NFE2L3; ELF5; SOX11; ELK3; ID4; EGR2; ID1; EMX2; EGR3; FOS; IKZF1; CEBPA