Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16741 Azd-8330 GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 25 ID2; TSC22D3; ZNF589; POU4F1; RBBP7; RBBP4; TOB1; HMGN3; PIR; TOX; ING2; MXI1; PEG3; TBX3; BRCA1; SAP30; HEY2; SMARCA2; SNAI2; TLE1; BTG1; ZBTB18; GATA3; ESR1; CRK
Down-regulation 54 FOSL1; MYC; ABL1; HMGA2; PPRC1; EGR1; SPI1; SOX9; ARID1A; ETV5; LOXL2; SMAD3; MED13; NCOR2; SIX2; ZFP36L1; STAT3; NRIP1; MAFF; BCL3; VPS72; RERE; TRIP6; IFI16; RUNX1; ZNF217; HIC2; NFE2; MEOX2; HHEX; IRF8; NFE2L3; MECOM; BHLHE40; NKX2-1; POU2AF1; WWTR1; ID1; RBPJ; NR4A1; TRIB3; ZNF331; FLNA; KLF4; ELK3; TCF4; EGR3; EGR2; TFAP2C; SOX11; PBX1; SMAD1; ID4; ARNT2