Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16739 Azd-8330 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 56 GATA2; ID2; TBX3; TSC22D3; FUBP1; SIX3; DMTF1; PHOX2B; TLE4; HAND1; SMAD6; TRPS1; TBL1XR1; DDX5; HMGN3; IKZF1; RAN; BAZ2B; E2F8; TP63; PRRX1; CAMTA1; ISL1; GATA3; SNAI2; ERBB4; ZFP36L2; NFIB; ZNF711; MEIS2; MYT1L; LIN28A; TRIM29; TOX; MKL2; PLAG1; HMGB3; RBPMS; GATA6; ID3; TFEC; ZNF512B; TLE1; SAP30; TXNIP; MEOX2; ELF5; EYA1; PBX3; TFAP2C; SMARCA1; MEIS1; ID1; FOS; HOXC6; CRK
Down-regulation 41 FOSL1; MYC; HMGA2; ABL1; FHL2; EGR1; HES1; MAFF; ZNF146; ZFP36L1; TSC22D1; KMT2B; HHEX; CEBPG; SATB2; LOXL2; WWTR1; SMAD3; SIM2; EGR3; FOXD1; TRIB3; STAT1; NRIP1; BCL3; FOSB; SAP18; SOX9; ELF3; IRF7; NKX2-2; NR4A1; KLF10; NR4A2; HOXB2; IRF8; CREB1; EGR2; PITX1; BASP1; PAX8