Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16734 Ldn-193189 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 45 TSC22D3; XBP1; FOXO3; RELB; ZNF131; RUNX1; HIVEP2; RNF138; SMAD3; KDM5D; NFKBIA; EGR1; FOXD1; KAT6B; ABL1; POU2AF1; TRIM22; SERTAD2; ZNF394; FOXO1; CEBPB; INSR; KLF10; BTG1; ZSCAN18; ZBTB16; THAP11; MYB; BASP1; ZFP36L2; BRD2; PAX5; CEBPA; CITED2; ESR1; TOB1; NR2F1; MAGED1; ASCL1; TXNIP; CREB1; ELF5; RUNX3; NR4A2; CRK
Down-regulation 67 NR2F6; ZNF143; ENO1; TBL1XR1; ID3; MLLT10; WIZ; YAP1; NUP62; SMAD6; RARB; ENY2; FOXM1; SNAI2; SIX2; SIX3; CRY1; SMAD7; SCAND1; RAN; NKX3-1; CDC5L; BANP; PITX1; NFAT5; CDIP1; CHD7; TGFB1I1; RBL2; TLE1; FOXF2; ZNF232; MECOM; CALR; ZNF22; ISL1; CARHSP1; LITAF; HMBOX1; SOX11; HOXD3; STAT4; ZBTB20; MEOX2; PITX2; DNMT3B; MEIS1; TBL1X; TLE4; HIPK3; TCF7L2; MEIS2; SATB1; ZNF423; ZFPM2; AHR; ZEB1; PBX3; TOX; EGR2; LEF1; DACH1; SMARCA1; ID4; FOS; ID1; IKZF1