Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16728 Cgp-60474 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 95 NFATC3; POU2F2; MYF6; CARF; LZTS1; TLX2; TBX1; TWIST1; ESR2; CEBPE; PRMT2; ZNF652; TGFB1I1; DLX5; SRCAP; HIC1; ENO1; ERG; DBP; NEUROG2; CERS6; FOXO4; ONECUT2; ADRB2; RARG; RFX2; VGLL1; RXRG; RFX5; CBX2; FOXN3; PHOX2B; HOXB13; PKNOX2; HMGN3; PRRX1; SCAI; ZNF419; SSX1; NEUROD1; MED14; BARX1; ZNF224; HDAC9; CARHSP1; FOXE1; SOHLH2; NANOG; SOX18; TCF4; ZNF667; RBFOX2; ARNTL2; NR5A2; ZIC3; ZNF512B; IL16; CHD3; CERS4; ZFPM2; SUMO1; TGFB1; CUX2; PITX2; MAGED1; SIX3; ZNF423; ZNF532; PAX6; AEBP1; NFAT5; TBL1X; HLF; NFE2; CIITA; KAT2B; BCL11A; HIRA; FLNA; ZBTB20; SOX2; ISL1; INSM1; EYA1; ZSCAN18; IRF6; WWC1; SATB1; BCL11B; POU2AF1; HOXD1; FOXG1; ELF5; ARNT2; EMX2
Down-regulation 135 MYC; NFKBIA; FOSL1; HES1; FHL2; NFIL3; TBP; EED; HOXA5; SUV39H1; HOXA10; CCNA2; ZFP36L2; XBP1; ARID4B; PLAGL2; CEBPD; HMGXB4; ETS2; ELF1; PPRC1; TBPL1; CEBPB; RLF; TAF5; KAT6A; BCL10; DR1; CEBPG; EGR1; VEZF1; MAFF; MED6; MED17; TGS1; USP22; SMAD3; ZNF195; ZNF14; TSC22D2; ZNF443; RBM39; JUNB; ZNF430; ZNF146; TFCP2L1; NRIP1; YAF2; SAP30; TRIM27; BASP1; KLF6; E2F6; ZNF410; ZNF267; HMGB3; UIMC1; CTCF; RNF138; BRD4; SSRP1; ADNP2; MTF2; ZBTB11; PUF60; RCOR1; MAML1; BTG1; THAP1; ING2; CHD7; TAF1A; BAZ1B; ATF7IP; SIAH2; FOSB; TAF1D; PSPC1; CREG1; SOX9; ELK3; NRBF2; ID1; ZNF12; FOXC1; ARNTL; ZNF107; SUB1; ZFP36L1; ZBTB1; ZNF189; SOX4; AFF1; SP3; TSC22D1; BRD2; ABL1; TCF7L2; BMI1; CBFB; FOXJ3; EGR2; ZNF281; MYB; TOB1; EGR3; RREB1; HMGA1; HIC2; CRK; JUN; SMAD7; TFEC; NR2F2; GATA6; SATB2; CTNNB1; DNMT3B; BAZ1A; FOXO1; BHLHE40; HOXB7; KLF4; IRX5; TRIM16; CITED2; TGIF1; KLF10; AHR; TXNIP; ZEB2; ATF3; CEBPA; HOXC6; PAX8