Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16727 Cgp-60474 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 80 MDM4; MZF1; LZTR1; ZNF224; MTA2; EZH1; HDAC5; ADRB2; CERS6; GTF2I; STAT2; HDAC9; CARF; TGFB1I1; CALCOCO1; FOXO4; EHMT2; PBX2; SP140L; ZNF345; ZNF688; L3MBTL1; GRHL2; ZNF667; ZNF467; RBBP5; CNBP; ZNF652; MAZ; NR1H2; CBFA2T3; AEBP1; TCF7L1; BBX; TCEB2; HMGN3; ZSCAN18; NR5A2; MED14; CERS4; TGIF2; TCEA2; TBL1X; NFATC4; FOXF1; GLI2; TCF4; SOX2; ZNF611; ZNF117; SUMO1; ZFHX4; NANOG; KAT2B; MAF; MEOX2; TWIST1; ZNF160; PRRX1; ZNF91; ZNF665; ZNF589; TCF21; FOXF2; BCL11A; SHOX2; DLX5; GTF3A; CREB1; JUP; INSM1; ZNF512B; ELF5; SOX11; MEIS2; SOX17; PBX1; ARNT2; SMARCA1; SSBP2
Down-regulation 119 MYC; FOSL1; NFKBIA; HES1; SUV39H1; TBP; NFIL3; CCNA2; HOXA5; NUP62; XBP1; HOXA10; CEBPB; FHL2; EED; ZFP36L2; NRIP1; JUNB; POLR3F; SETD2; KAT6A; CEBPD; ARID4B; TRIM32; RNF138; TAF5; HMGA2; BASP1; ZBTB24; NPAT; E2F3; MAFF; VEZF1; ADNP; BLM; SMAD7; MED17; ABT1; ELF1; TGIF1; NKRF; SMAD3; EGR1; PPRC1; FOXJ3; MED7; EGR3; DPF2; HSF2; SNW1; TSC22D2; RELA; PLAGL2; CCDC59; ETS2; TOB1; TFAM; ZNF267; CHD1; RREB1; FOXC1; JUN; AFF1; HOXA1; ELK3; SATB2; BRD3; JARID2; ZNF146; NFKB1; RNF111; MED6; BAZ1A; RBM14; SF1; BHLHE40; SAP30; HMGB3; KLF2; RLF; AHR; CRY1; KLF10; SUB1; ZNF189; CCNE1; KAT7; SIX2; TLE1; TSC22D1; ZBTB1; KLF6; ZNF217; NRBF2; EGR2; NR4A1; NR4A2; CREM; SOX9; MLXIP; DNMT3B; IRX5; ZBTB38; NR4A3; HOXB7; SOX4; ATF3; MYB; SALL1; ID1; RUNX3; ZFP36L1; SATB1; KLF9; MAFB; ZEB2; TXNIP; GATA3; CEBPA