Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16726 Nvp-aew541 GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 107 TWIST1; NR1D2; FOXJ2; CREB3L2; BTG1; CITED2; ZNF93; IFI16; PRDM14; ZNF652; DDIT3; ZNF264; E2F5; ZNF665; TEAD3; ZNF623; ZNF3; SNAI2; GLI2; NLK; BBX; RXRG; ZNF175; BNC2; ZNF394; ZIC3; DBP; ZNF43; TCF7L2; ZNF232; SPIB; ZNF573; POU2AF1; LIN28A; IRF9; ZNF711; TRIM24; TCEA2; CEBPG; JUN; ZNF667; HMGN3; TXNIP; PRRX1; CBX4; SMAD3; RBFOX2; SIX3; FOXC1; SIX2; NR1H4; ZNF415; NANOG; CNBP; SALL2; CNOT3; PBX1; TERF1; ZNF329; GATA6; CREB1; KLF4; EYA1; NFATC4; ZNF611; HEY2; TCF7L1; DLX2; NEUROD1; MEIS2; ZNF544; ZNF160; ZNF91; ZNF117; ZFHX4; KAT6B; TCF4; ZNF423; CREM; HOXA1; PLAGL1; ZNF512B; TGFB1; BACH2; TFAP2C; PAX6; SOX2; ZNF721; ELF5; FOXD1; HIRA; PAX5; FOXG1; SOX11; TRIM29; BHLHE40; PBX3; ARNT2; CEBPA; ID1; ZHX2; INSM1; MAFB; SMAD1; HOXD1; BHLHE41; HEY1
Down-regulation 31 IKBKAP; ARID4B; RNF6; HDAC1; NUP62; E2F3; TSC22D1; MSC; TAF1D; FOSB; CRY1; LPIN2; ASCL1; CBX3; CTNNB1; NRIP1; IRF8; SPEN; OLIG2; HMGB3; ZBTB18; ELF1; GTF3A; SATB1; EYA2; TRIP6; CRYM; BASP1; PEG3; EMX2; PAX8