Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16725 Nvp-aew541 GSE70138 MCF10A Human 3h 0.12uM EID0008
Types Number Response transcription factors
Up-regulation 33 GATA2; KDM5D; E2F2; PHF20; TSC22D3; ISL1; NKX3-1; ZFP64; ID3; ID1; LPIN2; TFDP2; SMAD6; ID2; KAT6B; BATF3; NRBF2; KLF2; ELF1; TCF21; PFDN5; SMAD7; COPS2; ZFP36L2; MEIS1; TOX; SOX4; PEG3; BHLHE40; PITX1; NR2F2; ZEB2; EGR2
Down-regulation 36 KDM5C; ZNF124; EN1; ZSCAN31; MED6; CHD7; TCF7L1; TGFB1I1; SUB1; EGR3; ZNF117; SIX3; ZNF160; ZNF665; ZNF91; CRK; CTBP2; IRF8; BHLHE41; MLXIP; ZKSCAN1; HLX; SATB1; LOXL2; ZIC1; PBX3; TOX3; TFAP2C; ZBTB18; FLI1; MEF2C; ZHX2; PBX1; HOXB2; POU2AF1; CEBPA