Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16722 Nvp-aew541 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 70 TSC22D3; VGLL4; BTG1; EN1; ZNF589; ETS2; MYCL; ZSCAN31; BRD8; ZNF302; ZKSCAN7; ZNF160; KLF9; POU5F1B; TDP2; PRPF6; ZNF22; SNAI2; PROX1; HBP1; PNRC1; MECOM; TP63; ZNF721; KLF5; EHF; TBX2; RERE; PLAG1; BCL11A; ZNF611; PLAGL1; ID3; WWTR1; PRRX1; KAT6B; ID4; TRIM29; PITX2; ZNF665; ZNF232; DACH1; RBPJ; TWIST1; TRIM22; SOX17; TCF7; ZEB1; TULP3; HOXA5; KLF4; TSC22D1; DLX5; KLF6; MYB; ID1; SOX2; ZBTB20; IRF7; MAF; TXNIP; CEBPA; CREB1; PBX1; TCF4; ZIC1; HOXD1; SMAD1; POU2AF1; ARNT2
Down-regulation 28 FOSL1; MYC; RRN3; NUP62; STAT4; ETV5; SUB1; BATF3; JUN; GATAD2A; CRY1; HSF2; ELK3; MYBL1; MYT1L; MYRF; PEG3; MKL2; FOXD1; MLXIP; THAP11; NKX3-1; MXI1; KDM5D; SATB1; FOS; GATA3; PAX8