Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16721 Nvp-aew541 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 77 TSC22D3; NR1H2; KDM5A; ZNF432; FOXO3; SP110; PNRC1; JUP; MKL1; IFI16; SMAD4; TLE4; EP300; SNAI2; DDIT3; BTG1; TRRAP; PBXIP1; PRKDC; HBP1; TCF4; ZBTB16; IRF8; SREBF1; MAF; KLF2; NCOA2; TRPS1; UBE2B; PBX3; BACH1; SPIB; ZNF721; IRF9; ZNF587; NANOG; PEG3; CEBPB; RAD21; IRF7; KAT6B; KAT7; ZNF217; ZNF160; FOXO1; RERE; FOXD1; KLF6; HMGB3; BRCA1; SHOX2; BACH2; SCAND1; GATA3; TXNIP; HLX; ARID5B; HHEX; KLF11; PAX5; BHLHE41; JAK2; TCF7; ZBTB20; TWIST1; MAFB; CITED2; AEBP1; FOS; PIR; WT1; POU2AF1; BHLHE40; TFAP2C; ATF3; HOXC6; CRK
Down-regulation 40 FOSL1; ZNF146; MYC; HES1; DNAJC2; PPRC1; EED; ZSCAN31; PMS1; KMT2B; NR2F1; ZNF22; ZNF302; ZKSCAN7; ZNF12; EHF; RREB1; MYCN; ZNF195; ZNF529; SIX1; CBX6; NRIP1; ZEB1; EYA2; TAF10; ZBTB18; CRYM; RBPJ; ELK3; SMAD7; DACH1; EMX2; MYT1L; MXI1; NKX3-1; SMARCA1; TCFL5; CEBPA; PAX8