Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16718 Pf-431396 GSE70138 MCF10A Human 3h 0.37uM EID0008
Types Number Response transcription factors
Up-regulation 50 ZNF586; ZNF134; ZNF211; ARID5B; CERS6; ZNF551; ZNF587; ID2; FOXA2; ADNP2; ZNF419; ID3; ZNF264; PLAGL1; ZNF329; ZNF304; TOB1; CRY1; HMGN3; HIVEP1; PAX6; ZNF652; ZNF44; ISL1; POU4F1; ID1; ETS2; SMAD6; KAT6B; IRF4; BHLHE40; ZFP36L2; HMBOX1; MECOM; TXNIP; ZNF217; SMAD5; FOXD1; SATB2; FOS; FOXG1; TCF21; JUP; TOX; ZNF91; FOXF1; CREB1; KDM5D; PEG3; MEIS2
Down-regulation 39 ASCL1; STAT3; PTRF; FOXK2; DEAF1; EN1; OLIG2; TAF10; HOXC10; ADRB2; FOXC1; BAZ1A; IFI16; FOXE1; MYBL1; BHLHE41; CTBP2; HMGB3; ELF5; POU2AF1; HEY2; SOX10; TFAP2C; SHOX2; EGR3; EGR2; KLF4; OSR2; ID4; ZEB2; MAFB; ESR1; BASP1; CRK; PBX3; WT1; EMX2; PAX8; CEBPA