Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16717 Pf-431396 GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 53 ECD; ZMIZ1; MDM4; JUN; RBBP5; ID2; TCF7; CNOT2; INSM1; ASCL1; SP110; NR5A2; NANOG; CAMTA1; SPDEF; MTF2; SPIB; AEBP1; HMGN3; SOX2; SOX9; MBD2; BTG1; HMBOX1; CTNNB1; TRIM22; MDM2; SOX4; AES; TBX3; PAX6; SSX1; BRD2; FOSB; DLX2; HEY1; ZNF721; BRD4; TRPS1; FLNA; KDM5D; ZBED2; LMCD1; TFAP2C; PBX3; BHLHE41; ESR1; SATB1; LEF1; MSX1; ID1; MEIS2; ARNT2
Down-regulation 24 ATF5; CTBP2; NCOA6; ZBTB38; SMAD3; BASP1; ADRB2; VPS72; CITED2; RXRA; HMGB3; TAL1; ZSCAN18; NFE2; MXI1; TGIF1; EGR1; ZBTB18; TOX3; WT1; ZEB2; EMX2; CEBPA; PAX8