Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16716 Pf-431396 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 66 TSC22D3; JUP; ID2; SPDEF; TOB1; SMAD2; EGR1; CIITA; KLF1; TSC22D1; NFIL3; NCOA2; TAL1; IKZF1; RARA; ZNF467; C1D; LEF1; SMARCD3; IRF4; VDR; MXD4; BRCA1; SP110; FOXD1; IL16; ZBED2; ZNF200; SMARCA2; FOSB; TXNIP; PNRC1; LYL1; MLXIP; FOXO1; ZMYND8; SSX1; NAB1; ID3; MITF; MEF2A; SNAI2; PAX8; EGR3; HOXB2; MYRF; MKL2; WT1; HLF; HOXA5; AFF1; MNDA; BHLHE40; PLAGL1; KDM5D; FOS; TLE4; NR4A2; AHR; SOX4; EMX2; KLF10; HOXC10; ATF3; MAFB; HOXC6
Down-regulation 49 MYC; MED13; ADRB2; NFIB; ZNF334; WWTR1; SALL2; MYBL1; PAXBP1; TERF2; TCF7L1; BLM; JUN; ELF5; PAX6; ATF4; ZIC1; ZNF22; CAMTA1; DACH1; SUB1; ZNF43; IRX5; CBFB; NEUROD1; ZEB1; ZBTB38; FOXF2; TP63; SMARCA1; SCAND1; TLE2; THAP11; ZNF160; ELK3; MXI1; REL; PBX1; TBX3; TRIP6; TFAP2C; MSX1; CRK; HEY1; SOX11; CREB1; MEIS2; TBX2; CEBPA