Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16715 Pf-431396 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 61 ZNF835; NR2F1; NFKB2; ARNTL2; POU5F1B; ZNF589; STAT2; CNBP; SMAD6; PRRX1; ZSCAN18; DEK; ZNF467; FOXF1; OVOL2; MECOM; NFE2L3; HDAC1; ZFPM2; TGFB1I1; HEY2; HOXB2; HOXC4; SOX2; TAL1; MYCL; NR1H4; KAT2B; ZNF423; WWC1; VPS72; TRIM22; DLX5; SOX4; ZNF83; CEBPA; LOXL2; ASCL1; PAX8; SMARCA1; ZNF512B; HOXC10; HOXB6; NFIB; ID4; EYA1; EMX2; FLNA; ERBB4; ESR1; HEY1; TCF4; AEBP1; MAF; TRIM29; DACH1; PBX3; BHLHE40; ZNF91; ARNT2; ID1
Down-regulation 146 MYC; FOSL1; SUV39H1; HES1; NFE2L2; CEBPB; ADRB2; ARID4B; FHL2; NFKBIA; TSC22D2; EED; MED17; NFIL3; PLAGL2; ZBTB11; USP22; KAT6A; TBP; ADNP; ZNF473; PPRC1; CHD1; NRIP1; BCL10; SNIP1; CCNA2; E2F6; RNF6; ZFP36L2; BRPF1; ING3; CEBPD; FOXO3; SERTAD2; XBP1; MED13; ZBTB24; MAFF; ZZZ3; RLF; ZNF267; VEZF1; RRN3; TGS1; ABL1; HSF2; TAF1A; THAP1; JUNB; HMGXB4; ZNF394; ZNF14; ZNF12; ERF; MTF2; RNF4; RCOR3; ZBTB16; CHD7; NFYA; ADNP2; ZNF574; ZNF263; TAF1D; HTATIP2; RNF138; MED1; BTG1; TMF1; BLM; PHF8; PATZ1; CCDC59; KMT2A; ZNF184; E2F3; ZBTB1; ZNF443; TOB1; IKZF5; ELF1; ING2; HOXA5; SF1; BATF3; RNF111; ZNF200; BATF; ZNF189; SMAD3; ZNF7; TRIM32; ARID1A; STAT4; IRX5; HOXA1; ZNF107; MYBL1; TOPORS; DDIT3; FOXJ3; ZNF124; SNAI2; JUN; JARID2; EGR4; FOXD1; ZNF281; SATB2; PIAS1; CCNE1; RUNX3; KLF10; BRD2; BCL3; KAT7; BMI1; KLF6; STAT1; FOXO1; SIX2; IRF4; NR4A3; ETS2; AHR; KLF2; MKL2; TGIF1; MYT1L; TSC22D1; BAZ1A; RREB1; SAP30; ZBTB38; SMAD7; EGR3; ZBTB20; JUND; AFF1; NR4A2; EGR2; MYRF; BASP1; ZEB2; E2F2