Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16710 Gsk-1059615 GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 81 PPARG; TSC22D3; ID2; EZH1; HBP1; NR3C1; TRAK1; MZF1; FOXO3; BRCA1; USP21; ZBTB16; TADA3; FOXO4; CEBPD; ZNF93; FOXN3; CALCOCO1; NFE2L1; INSR; TWIST1; EP300; ZNF532; CNBP; SOX4; PNRC1; HDAC5; ZNF224; ZNF500; BTG1; SMARCC2; ZBTB20; RAD21; L3MBTL1; ZNF43; ZNF573; KLF7; ZNF423; ATF4; KLF13; ZMYND8; JUP; PAX6; TXNIP; MBD2; ZNF160; GTF2IRD1; PBX3; HMBOX1; PIAS1; NR1D2; HOXA5; FOXO1; HOXB5; ZNF721; HOXB6; NEUROD1; TCF4; ZNF117; TCF7L2; KLF11; ARID5B; MYCL; ZIC1; KLF9; INSM1; MEOX2; BCL6; TULP3; ZNF91; NANOG; ZFPM2; KLF5; CREB1; PBX1; HOXD1; MECOM; ARNT2; MYB; ID1; MEIS2
Down-regulation 48 FOSL1; MYC; TBP; FHL2; HES1; HMGA2; ADRB2; HOXA10; EGR3; EGR1; MED7; XBP1; EGR4; TFAM; ELK3; KLF10; RNF14; BHLHE40; RNF141; WWTR1; NFE2; NKX3-1; RREB1; NR0B1; CD3D; HOXC10; RUNX1; FOXC1; SATB1; JUN; SATB2; POU4F1; STAT4; MAGED1; BAZ1A; CRYM; EGR2; TFEC; FOXF1; BCL11B; TSC22D1; PITX1; TOX; ZEB2; LEF1; ID4; HOXC6; CEBPA