Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16709 Gsk-1059615 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 66 TSC22D3; HMGN3; FOXO3; EZH1; HBP1; NR3C1; BTG1; HDAC5; NFE2L1; PNRC1; CALCOCO1; IRF9; ZBTB16; PHIP; TCF4; ZBTB17; CDK9; STAT3; TXNIP; ID2; TRIM24; BBX; KLF9; KLF13; HOXA5; SOX4; MBD2; TOB1; NAB1; TCF7L1; COPS2; RAD21; FOXA1; ASCL1; ARID5B; FOXN3; PIR; EYA1; TRPS1; JUP; ZNF423; PBX3; TWIST1; ZNF331; INSM1; AEBP1; FOXO1; CENPF; TRIM29; MAFB; MEIS2; RBPMS; CREB1; PBX1; ISL1; FOXG1; ZHX2; TSC22D1; MAF; ZNF91; HOXD1; ARNT2; GATA6; ATF3; HOXC6; CRK
Down-regulation 59 FOSL1; MYC; FHL2; TBP; ADRB2; HMGA2; PPRC1; HES1; HOXA10; EGR1; NFE2; ZNF23; ECD; EGR3; GFI1; ELK3; RREB1; HOXB7; ENO1; MNDA; GCFC2; ZNF516; BATF3; SMAD7; HOXB6; SATB2; FOXA2; BHLHE40; POU4F1; CCNH; EGR4; PSIP1; PEG3; DNMT3B; KLF10; TRIB3; CEBPZ; BAZ1A; STAT4; VDR; MYT1L; RUNX3; KLF4; CD3D; LYL1; TLE1; SATB1; ZEB1; EMX2; NR2F2; HOXC10; LEF1; PITX1; BASP1; TOX3; KDM5D; ZEB2; WT1; CEBPA