Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16708 Barasertib-hqpa GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 39 ZNF274; RFX5; ING3; CDX1; GFI1; HOXA11; POU2AF1; PAX5; ADRB2; ZNF536; PTTG1; ASCL1; TXNIP; CHD7; SP140; BRCA1; HDAC9; ZFP36L2; LYL1; ZNF107; SATB2; ISL1; KLF10; FOXF1; BASP1; BTG1; BNC2; OSR2; MNDA; IRF4; BCL11A; KDM5D; CEBPA; SOX4; SNAI2; HLTF; RXRA; GATA6; ZEB2
Down-regulation 36 HMG20B; ATF5; NFIB; YAP1; ZNF22; JUND; STAT4; ARNTL2; BANP; SIAH2; NRIP1; ZNF573; GTF3A; TCF7L2; CALR; TAF10; KLF6; CEBPB; SMARCA1; MECP2; ERBB4; BRD4; ERG; TLE1; TWIST1; HOXB2; CENPF; KLF9; AHR; TCF7; SATB1; SOX11; HOXC6; ZNF91; ESR1; IKZF1