Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16705 Barasertib-hqpa GSE70138 MCF10A Human 3h 1.11uM EID0008
Types Number Response transcription factors
Up-regulation 30 YAF2; DEAF1; TBX2; ARNTL; RNF14; IKZF1; MBD2; ZNF226; BHLHE41; HMGB1; TOB1; NR2F1; CBFB; ASCL1; FOXA1; KLF6; FOS; NKX2-1; ZFP36L2; MYBL1; CEBPA; TXNIP; NFIB; IRX5; KLF9; INSR; FOSB; BASP1; HOXC6; CRK
Down-regulation 19 ZNF423; SIX2; SP3; ERBB4; MYCN; BNC2; SMAD6; MAFB; MEIS2; IRF8; RXRA; ZHX2; SOX17; CREB1; BCL11A; EMX2; MYRF; PBX1; PAX8