Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16704 Barasertib-hqpa GSE70138 MCF10A Human 3h 3.33uM EID0008
Types Number Response transcription factors
Up-regulation 31 ZNF274; TGFB1I1; ZNF131; TCF12; HMGA1; KLF7; ERG; NFKB1; TCF21; ZBTB18; ESRRG; ESR1; NFIB; IRF7; BCL3; KAT6B; ELF3; MECOM; BHLHE40; RBPMS; ELK3; RYBP; MSX1; LMCD1; KLF2; ZNF281; EYA2; KLF10; IRX5; SOX17; CRK
Down-regulation 30 CENPB; IKBKAP; ASCL1; MAGED1; HIC2; ZBTB38; PBXIP1; SIX3; RBL2; NKX2-2; MAF; BCL11B; RXRA; ZMYND8; FOXE1; TLE1; MYCL; IRF8; KLF5; CD3D; POU2AF1; ZNF160; FOXO1; MEOX2; TXNIP; TCF4; SATB1; SSBP2; BASP1; CEBPA