Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16703 Barasertib-hqpa GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 49 SSBP2; MITF; TBL1XR1; ARID5B; ZFP36L1; ATF3; MECOM; REST; MXD4; JARID2; HOXB7; BHLHE41; TBX2; ZBTB20; EGR1; ZNF107; PAX8; CBX3; HOXC4; TAF1D; PURA; EMX2; TLE4; CENPF; OSR2; CBFB; ID3; SALL1; IRF4; IFI16; MEOX1; RBPMS; HOXB6; ID4; CITED1; NR2F2; ZNF217; FLNA; LEF1; HLTF; SNAI2; HOXC6; CREB1; SMAD1; TFAP2C; MAF; TXNIP; MAFB; CRK
Down-regulation 31 NFATC4; NR1I2; NHLH2; RARG; GATA6; ZNF394; ZBTB16; ZIC3; RUNX1; MYB; IRX5; RORA; BCL11A; LIN28A; CRYM; KLF10; CD3D; DACH1; HLX; PLAGL1; MYBL1; SATB2; KLF2; MXI1; PBX3; TOX3; MEIS2; ARNT2; GATA3; IKZF1; CEBPA