Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16702 Vemurafenib GSE70138 MCF10A Human 3h 0.04uM EID0008
Types Number Response transcription factors
Up-regulation 51 ZMYM2; MNAT1; NFKB2; JUN; TBX3; HDAC9; TAF10; ARNTL; MSX1; JARID2; PAX8; CNOT2; CBX6; BRCA1; IKZF1; KDM5D; ESR1; SNAI2; NAB1; GATA3; HMGN3; ZFP36L1; WWC1; IFI16; KLF6; BHLHE40; SALL1; CTNNB1; SMARCA2; HOXC6; ZBTB38; FOSB; SHOX2; HOXB2; SMARCA1; MAF; BTG1; CEBPA; PIR; HOXC10; RUNX3; NR2F2; RXRA; BASP1; BHLHE41; MAFB; EMX2; WT1; SOX17; KLF4; CRK
Down-regulation 50 ARID4B; RCOR3; MED17; HOXA5; CAMTA1; SMAD4; BCL10; HOXA7; NR2F6; NR5A2; PBX3; ERG; ZNF423; NR4A1; HLX; ZNF200; NANOG; CDX1; INSM1; ZNF12; GATA6; TGFB1I1; FOXF2; NR4A2; TOX3; SOX11; ZBTB20; FOSL2; TLE4; HMBOX1; TCF21; ZNF331; FOXF1; ZNF551; MEIS2; KLF2; HMGB3; POU2AF1; NR4A3; MNDA; INSR; HOXD1; ST18; AEBP1; ZKSCAN1; BCL11A; PBX1; MYRF; EGR2; FOS