Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16697 Vemurafenib GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 35 TSC22D3; XBP1; SPDEF; NFIL3; ATF4; SP110; PQBP1; PAWR; IRF4; TRIB3; ZMYND8; IRF7; SNAI2; IL16; BHLHE41; ZBTB16; BTG1; POU2AF1; ZHX2; EHF; NFE2L3; JAK2; MYRF; LYL1; JUP; BNC2; ATF3; SOX4; AEBP1; TFAP2C; WT1; ARNT2; PBX3; EMX2; HOXC6
Down-regulation 40 ATF5; HMGA2; SOHLH2; ARID4B; ADRB2; JUNB; PLAGL2; RNF4; SCAND1; EYA2; ZBTB1; NRIP1; NR1D2; SMAD7; MEIS1; ELK3; TCF7; TBX3; ID3; FOSB; BASP1; ID1; NFIB; MYBL1; SALL1; SMARCA1; BAZ1A; SATB2; ZIC1; ZBTB38; SMAD1; NR2F1; SATB1; AHR; DACH1; TOX; ID4; CEBPA; CREB1; TBX2