Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16679 Hg-5-113-01 GSE70138 MCF10A Human 3h 10uM EID0008
Types Number Response transcription factors
Up-regulation 91 RELB; TSC22D3; GLI2; ID2; CREB3L2; NFIL3; BNC2; HOXA4; POU5F1B; ATN1; MMS19; BNC1; HDAC5; DEAF1; FOXO4; PRDM2; EBF2; TCF4; NFKBIA; CALCOCO1; PRDM12; RORC; ENO1; ZNF226; PRRX2; PKNOX2; ID3; ING4; TAF6; SALL2; HOXA5; KLF7; FOSB; ADRB2; PLAGL1; FOXE1; STAT5A; ARNTL2; BARX1; SCAND1; ELF3; BCL3; PEG3; GRHL2; TRIM28; KLF6; FOXD1; RERE; ZNF239; ASCL1; ZBED2; NANOG; HOXB5; SPIB; PAX8; TEAD4; HOXB2; HOXC4; TRIP6; ID4; SOX17; PITX2; FOXL2; POU2AF1; ZSCAN18; BHLHE41; NKX2-1; ERBB4; IRF7; CRYM; ZFPM2; KLF4; ZNF423; IRF4; IRF8; SOX4; CREB1; ATF3; EMX2; ID1; BACH2; WT1; NR4A1; SOX11; PBX1; AEBP1; MAF; BCL11A; FOXG1; PBX3; ARNT2
Down-regulation 59 FOSL1; EED; TBP; MYC; ZNF473; TBPL1; TRIM32; CCNA2; HMG20A; BRPF1; NUP62; BTAF1; ARID4B; PHF2; SAFB2; CHD7; TSC22D2; GMNN; CDK8; PATZ1; RBBP5; DACH1; ZSCAN31; TFAM; CERS6; MED1; CBFB; TLE1; ELK3; CDC5L; ZNF551; ZNF281; JARID2; TGFB1I1; ZNF189; TOX3; SAP30; SNAI2; TBX3; FOXF1; PURA; BRCA1; ZBTB1; FOXA1; ISL1; ZBTB18; ELF1; TOB1; LEF1; BAZ1A; SATB2; GATA6; MXI1; AHR; TOX; MNDA; NKX3-1; CEBPA; IKZF1