Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16677 Geldanamycin GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 52 FOXL2; EGR2; SIRT2; TCF3; NRBF2; BATF3; OLIG2; ZNF623; HMBOX1; BRD4; TRIP6; BARX1; SOX2; DDIT3; KLF13; PLAGL2; ATF3; CBFA2T3; ZNF468; TCF21; RUNX3; RFXANK; NKX2-2; MEIS1; FOXF2; MYRF; TOX; ZNF195; FOXF1; PEG3; TAL1; ZBTB20; SSBP2; SPEN; NFATC4; ZNF131; VPS72; IRF8; ZFPM2; ZIC1; WT1; SMARCA1; ST18; TCF4; TLE4; HOXB7; NR2F6; HOXB2; HOXB6; HOXD1; TRIB3; ZFP36L1
Down-regulation 49 HMGA2; ELK3; SETD2; EGR1; MYC; NFKBIA; YAF2; TXNIP; ADRB2; CBX7; BTG1; TGIF1; EZH2; PCGF2; SSX1; JUNB; SMARCA4; NR2F2; ISL1; KAT6B; HIVEP1; HOXA10; JARID2; OSR2; FOSL1; TSC22D2; ARID4B; ZFP36L2; JAK2; ID2; KLF11; ELF5; TLE1; CCNC; GATA3; SCAND1; HLF; KLF4; RFX5; ABL1; HOXC6; EGR3; ZBTB18; HOXC10; NRIP1; KLF2; TOX3; BCL11B; MAFB