Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16675 Geldanamycin GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 16 DDIT3; PTTG1; RBPMS; NFE2L1; TRIP6; NCOA3; PIR; ECD; XBP1; ATF4; EHF; POU2AF1; HOXC10; TLE4; FOXF1; HMG20B
Down-regulation 88 ELK3; EGR1; NFIL3; PAXBP1; LHX1; JUNB; MYC; BACH2; ZBTB16; ZNF529; PBX3; ZNF281; SUPT4H1; FOSL1; ZBTB20; FUBP1; ATF5; ETS2; ERG; ZKSCAN7; SHOX2; ZNF711; HDAC4; ZFP36L2; SOHLH2; TGIF1; NFE2L3; GATA6; BCL6; NR1I2; ZIC3; ZNF107; FOXN3; IRF1; SOX11; MED13; HLX; ARID1A; NFKBIA; ZFPM2; DMTF1; FOXA2; SMAD7; INSR; HIC2; ID1; KLF11; IKBKAP; ZEB2; SIAH2; SATB2; BCL11A; TCF7L2; RREB1; MTF2; EGR3; TLE2; EGR2; KLF4; ZBED2; ADRB2; ZNF44; CHD7; PAX6; NFATC1; PEG3; GLI2; IRF6; DACH1; LMCD1; MNDA; ERBB4; LPIN2; TLE1; PAX8; BHLHE41; PAX5; TOX3; ZEB1; ID2; THAP11; ZSCAN18; ID4; MYB; IKZF1; MAFB; BCL11B; ZNF91