Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16673 Geldanamycin GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 265 MLXIPL; PCBD1; ZNF384; EMX2; RHOA; KAT7; ESR2; STAT2; SOX9; RBPMS; HMGXB3; ARID4B; TP53; MYCL; NFAT5; BATF3; RAX; ATF7IP; NR1I3; EN2; HMX1; SMARCD1; FOXA2; ZNF711; HMBOX1; STAT5B; ETV1; JUND; PAX9; ETV4; TRIP6; KAT2A; TAF6; PPARA; FOXL2; PBXIP1; SIX6; NFRKB; POU3F1; SOX11; TCF15; MYOG; NAB2; HEY1; PFDN5; ZNF212; ZNF646; ZNF771; GTF2IRD1; GCM1; PITX2; HNF4A; APBB1; ZNF692; SREBF2; ING4; PRDM13; ONECUT2; MED24; TFCP2; GATA4; MYCN; AIP; TLE4; ZNF34; PDX1; IRF9; OLIG2; MNX1; ZNF337; ZNF76; NOC2L; HSF4; TFAP4; BARX1; LHX1; CALCOCO1; FOXB1; HOXD13; MAX; ZFHX4; ASCL1; HOXC13; HOXB13; WIZ; HOXC11; ZNF814; SSX1; HINFP; SP4; TADA3; ZBTB32; EYA1; RORC; TFEC; ZNF444; PRMT2; EN1; NHLH1; HIPK2; ATOH1; TBX19; SIX3; LZTS1; NFIC; REPIN1; ZKSCAN3; MNDA; SHOX2; RERE; TGFB1I1; CDX2; ZNF133; ZNF10; FOXO4; TOX3; EGR4; EYA2; RXRB; BAZ2B; TFCP2L1; TOX4; AR; IRF8; FOXF1; ZNF177; CIC; MYRF; ETV5; ZNF287; HR; SSBP2; CERS4; LEF1; ALX3; DDX17; FOXI1; CITED1; CAMTA1; SIRT2; SATB1; NR5A2; POU2F1; ZNF154; PAX8; ZNF835; HABP4; HMGXB4; HDAC5; TCF7; FLI1; PSIP1; POU3F2; CRX; DDIT3; PMF1; SUPT4H1; PCGF1; TBPL1; FOXD1; ZMIZ1; ALX1; HOXA4; KDM4C; TSC22D4; ZNF432; EHMT2; THRA; SIRT7; ZNF74; MAZ; ZMIZ2; PCGF2; NR4A1; TBX3; CALR; ZNF506; NEDD8; HLTF; MSC; ERBB4; ZNF248; CREB5; BCL6; RUNX3; GATA6; ZXDC; NR1H2; MEIS1; MXD1; ZNF529; SALL2; NR0B2; PITX1; ILF2; ARRB1; CREB3L1; ZNF580; ZIC1; USP21; SPEN; NR1H4; ZBTB20; ACTL6A; CENPF; FOXF2; APEX1; WNT4; SALL1; MEOX2; CIITA; TRIM28; RARG; ID4; HDAC1; MEIS2; ZNF224; SNAI1; ZKSCAN1; KLF7; PEG3; ZNF175; ZEB1; INSM1; PROX1; TAL1; SMARCA1; NEUROD1; BACH2; MAF; NKX2-2; YEATS2; RELB; GLI2; VPS72; FOXG1; CD3D; NRL; RAN; NR0B1; HDGF; CHD9; PHF1; HOXB2; SSBP3; ZNF83; DBP; HOXB7; ZNF467; RLF; SPIB; MSX1; KLF4; MTA1; RBFOX2; NRIP1; ZBTB18; HLF; IKBKAP; TWIST1; HMG20B; EGR2; HOXD1; TRIB3; KLF2
Down-regulation 140 TFDP1; BRCA1; ELK3; ZFP36L2; PQBP1; NFYB; CCNH; UBE2B; TGIF1; ZBTB16; KLF10; THAP4; ATF5; MED4; ZBTB1; E2F3; TAF12; PPRC1; TERF1; MED7; PSMC3IP; NR2F2; ELF1; RNF14; PPP1R13L; MBD2; ID1; SP100; TAF1A; RNF6; PMS1; TCEB2; AEBP1; SIM2; BIRC2; RNF4; RUNX1; C1D; PHF20; COPS5; UBE3A; ZNF215; YWHAB; FOXO1; PEX2; HMGA1; ENY2; TRIM33; ETS2; BRD4; CSDE1; EGR1; CNBP; TOB1; CEBPG; CEBPB; DNAJC1; BCL10; CTBP2; BBX; NR1H3; SCAND1; MXD4; CEBPZ; AFF1; AATF; WWP1; ERG; TFAP2C; USP22; KAT6B; HMGN3; RNF138; IRF1; JUNB; SMAD2; MTDH; SMAD1; THAP1; NFIB; FOXJ1; ZNF131; RNF10; GTF3A; SFPQ; HNRNPD; ABL1; TRPS1; TDP2; FOXC1; TLE1; ZHX2; C1QBP; TBP; RREB1; SMARCC1; ID3; URI1; KLF5; ATF1; ZNF165; PIR; NCOA2; MNAT1; KLF6; TOPORS; PBX3; RBBP8; POU4F1; CTBP1; BRD2; CBFB; LMCD1; PDLIM1; INSR; TGIF2; PURA; CCNC; DAXX; NFKBIA; ZNF217; ZNF200; OSR2; MAGED1; RFX5; FOXJ3; ING3; THAP11; FOXO3; IRX5; WWC1; TBX2; HOXC6; ZNF43; HOXB6; PPARG; ZNF136; SNAI2; ESR1; ZNF184