Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16666 Withaferin-a GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 87 EGR1; CCNE1; MKL1; IRF4; BATF; EP400; KLF7; ELK3; PRMT2; CDK9; MAFG; TXNIP; SREBF1; ZNF536; IL16; SP140; NFE2L1; CREBL2; IKZF1; TAF9; TGIF1; TRIM32; ZNF512B; HSBP1; ARID4A; RFX5; HOXB2; FOXD1; CDYL; CAMTA2; KAT6B; HMBOX1; SRCAP; SOX2; SHOX2; RBL2; MLXIP; PAX6; YBX1; ZHX2; PRRX1; KAT2B; TGIF2; SMARCA1; HOXB7; FOXO1; ZNF671; ZNF124; ZNF253; NR0B1; FOXJ3; BLM; BACH2; NKX2-2; CREM; RAN; HEY1; SOX10; TCF7L1; INSM1; XBP1; ETS2; DMTF1; SIAH2; BASP1; CRY1; MEIS1; NFATC1; FOXF1; ZNF189; ZFHX4; HTATIP2; MTA1; MSX1; TGFB1I1; SPEN; ZSCAN18; FOSL1; HOXB6; RORA; ZIC1; MEIS2; THAP11; RBPJ; CREB1; TRIB3; NR2F6
Down-regulation 82 PUF60; TSC22D1; CREG1; MTF2; HDAC7; MMS19; VGLL4; YBX3; TEAD4; SUPT4H1; GTF3A; SETD3; TCEB2; RUVBL2; ZFHX3; SAP18; CRYM; WWP1; SMARCD3; ERF; SIX2; HHEX; RCOR3; ZMYM2; FOSL2; YAP1; DDIT3; HMG20B; WT1; CEBPZ; SUB1; EMX2; NPAS2; LEF1; FOXC1; NR2F1; ATF3; NFE2; RXRA; JUNB; CALR; E2F2; DACH1; MXI1; MNDA; CITED2; HMGB1; ZNF350; TAF9B; YWHAB; NR3C2; VDR; ZSCAN16; MYB; MAGED1; TDRD3; NR2F2; SOX9; PBX3; CTBP2; ZNF32; PIR; BHLHE41; KLF5; ARID5B; ZNF302; ZNF394; WWC1; ING3; MEF2A; TCF7L2; ZNF443; IFI16; LMCD1; TCF7; STAT1; ID4; HOXA10; SOX17; TBX2; MAFB; SNAI2