Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16665 Withaferin-a GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 79 NR3C1; ZNF586; IRF1; GATA2; SSBP2; KLF10; MED1; CHD1; PQBP1; SP2; TFCP2L1; ID3; TOX; ETS2; NR1H3; ELF1; PHOX2B; TAL1; ZNF83; SAP30; ELK3; BRD7; HEY2; TFEC; ATF3; FLNA; NR4A2; CCDC59; TBX2; PROX1; ERG; ZNF266; MTF2; UIMC1; HOXB7; JUNB; FLI1; KLF6; PIR; ZNF302; BASP1; NUP62; KAT6B; MNDA; ASCL1; BLM; ISL1; MYCN; ZFP36L2; WT1; HEY1; ZBED2; SFPQ; ABL1; HIC2; HLX; HHEX; HOXC6; ZBTB20; CHD7; DACH1; RAN; CREG1; GATA6; IRF6; USF2; HMGB3; TLE4; FOSL1; MEIS1; BMI1; HMGN3; ZEB2; EGR3; STAT1; KLF2; HOXB6; MAFB; TRIB3
Down-regulation 70 SLC2A4RG; CRK; ZHX2; MYBL1; EHMT2; TCF3; LHX2; HOXB13; SIX1; BRD4; BACH2; TADA3; PBX2; ZBTB16; HABP4; MEOX1; SATB2; NEUROD6; FOXA1; TGIF2; BRIP1; NR0B1; HLF; TCFL5; CBFA2T3; YAP1; RBBP5; TRIM24; MKL2; SOX11; SHOX2; IKBKAP; ZNF589; SMAD1; E2F2; BTF3; CUX2; PIAS3; CEBPD; GTF2F1; BCL11A; GLI2; ZKSCAN1; YWHAB; GATA3; PBX1; KLF9; PIAS1; NRIP1; RORA; TWIST1; BRD2; ID2; ZNF189; NR2F6; ARID5B; TCF4; POU2AF1; TRPS1; NFATC1; HOXC10; RBBP8; PEG3; ZNF91; ZNF184; ERBB4; ZIC1; THAP11; ID4; IKZF1