Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16664 Withaferin-a GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 35 EGR1; GABPB1; KDM5B; ELF4; KDM5A; CHD1; ZNF589; KDM2A; XBP1; JUND; ARID4B; ZNF84; CENPF; FLNA; ATF3; FOSB; SF1; SFPQ; ERBB2; NR4A1; RAN; RUNX3; JUP; PDLIM1; FOXM1; MTF2; ENO1; LOXL2; NKX3-1; HMGN3; THAP11; STAT1; TRIB3; SATB1; HMG20B
Down-regulation 47 HMGA2; NFIL3; MYC; PPP1R13L; BTG1; TSC22D3; TSHZ2; SAP18; ADRB2; NFKBIA; PROX1; KLF9; HEY1; HIPK2; PBX3; KLF5; E2F2; ZNF467; LIN28A; NFE2L3; ZBTB20; PRRX1; ZBED2; HOXA5; MYB; ZNF302; HDAC9; TCF7L2; IFI16; MEIS1; ZNF264; ASCL1; TXNIP; NRIP1; MAF; ID4; DBP; HOXA10; SNAI2; LPIN2; ZBTB18; NR1D2; PEG3; BHLHE41; IKZF1; BCL11B; BASP1